Coronavirus Epidemic Update 25: Vaccine Developments, Italy’s Response, and Mortality Rate Trends

welcome to another MedCram lecture on
the SARS cough to virus causing the kovat 19 disease this update is for the
25th of February 2020 and we’re gonna talk about Italy and China and then
vaccines this is gonna be kind of interesting when we get into that and
again here are the numbers that they are reporting so I’m simply reporting what
they are reporting and we’ve hit 80 thousand proper total deaths at almost
2700 total recovered 27,000 and so we’re up to a differential there of 10 times I
remember when that was almost on par in fact when it was even less than the
number of total deaths so whereas total deaths have leveled off we still have an
increasing amount of total recovery which is always a good thing let’s look
at the nucleus wealth site which I’ve found to have some interesting graphs
that are unique to it I’m gonna scroll all the way down here to the bottom
where they talk about the mortality rate or the case fatality rate and as we’ve
talked about there is a bit of a delay in measuring what the total cases are
right now compared to what the total deaths are right now there’s been a
question about whether or not you should delay the mortality accounts and look
back four days eight days or 12 days depending on how long it takes somebody
an average to die from the onset and in looking at those it’s interesting that
if you look at all of the cases outside of Wuhan in the rest of China you can
see here that if you look at a full 12 days out that the mortality rate or case
fatality rate reaches around the same asymptote as if you look at eight days
versus if you look at four days and that’s just under 1% if you look at who
Bay province which is where who Han is and you do the same sort of analysis it
all settles out again but not at just below 1% but just below 5% this kind of
makes sense if you think about the fact that inside who Bay where most of the
cases were their health care industry is going to be more overwhelmed and
therefore perhaps have a higher case fatality rate so you can take a look at
this site we’ll put the link to it in the description below we go
over to the world ometer as we have done in the past you can see similar numbers
here where I like to look as the active cases and the close cases of the closed
cases that we have 91% of recovered and been discharged and 9% deaths if we look
further on down we come to the latest updates for February 25th we can see
here that there’s one new death in South Korea another death on the diamond
princess two new cases in Italy and 60 new cases in South Korea possibly some
good news here in South Korea is that the 60 new cases that were seen today in
South Korea is a sharp decline in new cases compared to 161 and so this may be
that there might be a cluster in fact that’s what they’re saying that there’s
two clusters and that has to do with this church where they had met and this
may be the reason for the spreading and this accounts for over 50% of the cases
within South Korea let’s go over to another site this is my Reuters title
battle against coronavirus turns to Italy Wall Street falls on pandemic
fares over a thousand point loss on the Dow Jones on the 24th a couple of
interesting things here at kind of contrast what they did in China and
what’s going on in Italy of course in China things seem to be not rising as
fast and in Italy things seem to be climbing pretty rapidly and so they
talked here about China putting cities in lockdown Italian authorities are also
doing similar things sealing off the worst-affected towns closing schools
halting the carnival in Venice what they say here interestingly this is from
Reuters China’s actions especially in Wuhan the epicenter of the outbreak
probably prevented hundreds of thousands of cases said the head of the w-h-o
delegation in China Bruce Aylward the rest of the world to learn from the
lesson of acting fast they’re at a point now where the number of cure people
coming out of the hospitals each day is more than the sick going in he said the
surge of cases outside of mainland China triggered sharp falls in global markets
specifically in Italy as investors fled to safe havens and they talks about the
European equities markets he goes on to talk about the epidemic in
China peaking between January 23rd and February 2nd and they say has been
declining since dr. Mike Ryan the head of the w-h-o emergencies program told
reporters it is still possible to contain the virus and that it might
appear each year like the flu quote the virus may settle down into an endemic
pattern of transmission into a seasonal pattern of transmission or it could
accelerate into a full-blown global pandemic he said in Geneva on Monday and
at this point it’s not possible to say which of these realities is going to
happen goes on to talk about how the Trump administration is requesting a
billion dollars to deal with the corona virus now specifically what it is that’s
going on in China we’ve got China’s National Health Commission said that
while the rapid rise had been halted the situation was still grim he said over
3,000 medical staff have become infected most in hebei province surrounding Wuhan
probably due to the lack of protective gear and fatigue and we talked about the
fact that they a case fatality rate in Wuhan was higher than it is in the rest
of China we also talked previously about the fact that there was no protective
gear but we also talked about the need for sleep and the ability to sleep and
get rest and of course if there are a number of professional colleagues of
yours who are infected in quarantine that’s going to increase the load on you
that’s gonna make you more fatigued and hence we see videos of health care
providers in China collapsing and we hear a number of these physicians are
actually Sur coming to the virus so at this point excluding obaid mainland
China reported 11 new cases that’s the lowest since they started actually
taking figures On January 20th overall China reported 409 new cases on the
mainland down from 648 a day earlier there was a measure of relief it says
for the world’s second largest economy has more than 20 province level
jurisdictions including Beijing and Shanghai here we go
reported zero new infections whereas what’s going on outside of China while
things are taking off we’ve got 29 countries and territories
with a death toll of about two dozen according to the Reuters tally South
Korea 231 new cases making its total to 833 we see a couple of new countries
that have come to the table here Kuwait Bahrain Oman and Afghanistan they are
believed to be cases that have been to Iran in the past so a lot of things
going on it’s almost like a Tale of Two Cities it seems as though China has had
a huge hit but things may be on the verge of something different potentially
we’ll have to see and then we have Italy and South Korea which are taking off
want to talk briefly about another interesting article this is in the Wall
Street Journal we’ll put a copy of this link as well on the description below
this fascinating article which you will probably need to have a log in to read
it talks about this drugmaker moderna incorporated which has shipped its first
batch of its rapidly developed coronavirus vaccine to US government
researchers who will launch the first human tests of whether the experiment
could help suppress the epidemic originating in China now why is this
experimental well I encourage you to actually watch the video that is on this
site and you’ll see what I’m talking about but very briefly let me explain to
you what it is that’s going on there okay so normally what happens is a virus
here’s the virus goes in and infects a cell and what happens is these proteins
go on the surface of the cell when this virus infects the cell these proteins
here are very important because it tells the body that this is an infected cell
or that this for instance is a virus and what they normally do is they will
normally take the virus and they will inactivate it or kill it and they will
inject it in and what will happen here is that these proteins will induce an
antibody response in the body that allows the body to have many of these
antibodies already ready to fight so this is the normal
situation up here and the problem is it takes many months to create this type of
model where you can inject these proteins into the body so that you can
have these antibodies form against these proteins what they’re planning on doing
from what I’m getting from this article is something completely different in
terms of a vaccine what they’re really doing here is they’re having a cell and
because they have the genome of this virus they’re able to inject in this
case the RNA somehow into the body and this RNA will then go into the cells
which will tell the cells to produce the antigens which will then cause the
antibodies to form against it so in other words instead of having the virus
or the lab produce these antigens to inject into the human so that the human
can make antibodies what they’re instead of doing is isolating the genomic
sequences themselves having them tell your own cells to produce these antigens
and then these antigens are going to cause antibodies to be formed and that
is how they can do this much faster because they don’t have to go through
all the sequences of having this be done in other words making this they can have
your cells make the vaccine for you and then have you self immunized against the
virus and it seems as though this really hasn’t been done before and so according
to that Wall Street Journal article it looks as though they’re going to be
starting clinical trials in April and so that would be three months from the time
that they learned about the genome to the point where they can actually get a
vaccine for human clinical trials now this is a new technology and for some
people this may sound really cool for others it may be well what are the side
effects of this what’s going to happen when you’re starting to put DNA or RNA
and structions messenger RNA in most cases
in this case into your cells and tell them to make proteins that are foreign
to your body to cause an immune response it almost sounds like an autoimmune
condition so it’s gonna be interesting to see what happens and what are the
side effects of this to get a better understanding of this you’re going to
need to know about molecular biology and as it just so happens we have a video
that’s a primer on molecular biology because what we’re about to do is get
into the details of the corona virus life cycle and what it actually does in
the cell and how it’s different from other viruses thanks for joining us

100 thoughts on “Coronavirus Epidemic Update 25: Vaccine Developments, Italy’s Response, and Mortality Rate Trends

  1. Please subscribe to receive notifications about new MedCram videos.
    Visit us at for clear explanations of over 60 medical topics.
    All links referenced in this video are in the video description.
    Quick links to our other videos on Coronavirus (COVID-19):
    – Coronavirus Epidemic Update 24: Infections in Italy, Transmissibility, COVID-19 Symptoms:
    – Coronavirus Epidemic Update 23: Infections in Kids & Pregnancy, South Korea, Spillover From Bats:
    – Coronavirus Epidemic Update 22: Spread Without Symptoms, Cruise Quarantine, Asymptomatic Testing:
    – Coronavirus Epidemic Update 21: Antibodies, Case Fatality, Clinical Recommendations, 2nd Infections?:
    – Coronavirus Epidemic Update 20: Misinformation Spread, Infection Severity, Cruise Ship, Origins:
    – Coronavirus Epidemic Update 19: Treatment and Medication Clinical Trials:
    – Coronavirus Epidemic Update 18: Cellphone Tracking, Increase in Hospitalizations, More Sleep Tips:
    – Coronavirus Epidemic Update 17: Spike in Confirmed Cases, Fighting Infections with Sleep (COVID-19):
    – Coronavirus Epidemic Update 16: Strengthening Your Immune Response to Viral Infections (COVID-19):
    – Coronavirus Epidemic Update 15: Underreporting, Prevention, 24 Day Incubation? (COVID19):
    – Coronavirus Epidemic Update 14: Hospital spread of infection, WHO allowed in China, N-95 masks:
    – Coronavirus Epidemic Update 13: Li Wenliang, nCoV vs Influenza, Dip in Daily Cases, Spread to Canada:
    – Coronavirus Epidemic Update 12: Unsupported Theories, Pneumonia, ACE2 & nCoV:
    – Coronavirus Epidemic Update 11: Antiviral Drugs, Treatment Trials for nCoV (Remdesivir, Chloroquine):
    – Coronavirus Epidemic Update 10: New Studies, Transmission, Spread from Wuhan, Prevention (2019-nCoV):
    – Coronavirus Epidemic Update 9: Fecal-Oral Transmission, Recovery vs Death Rate:
    – Coronavirus Outbreak Update 8: Travel Ban, Spread Outside of China, Quarantine, & MRSA:
    – Coronavirus Epidemic Update 7: Global Health Emergency Declared, Viral Shedding:
    – Coronavirus Outbreak Update 6: Asymptomatic Transmission & Incubation Period:
    – Coronavirus Update 5: Mortality Rate vs SARS / Influenza:
    – How Coronavirus Kills: Acute Respiratory Distress Syndrome (ARDS) & Treatment:
    – Coronavirus Update 3: Spread, Quarantine, Projections, & Vaccine:
    – Coronavirus Symptoms, Diagnosis, Treatment:
    – Coronavirus Outbreak – Transmission & Updates:

  2. Hi Doc. Been watching your videos since the coronavirus started and I badly need your help at this time. If you are to give an information to nonmedical people within 30mins, what will be the significant details that you will provide for these people to gain better understanding about the virus? Hope you will respond. Thank you so much.

  3. Iran is the worry. It's been under crippling sanctions for decades including medical supplies they are very vulnerable. The mortality rate seems to be higher there

  4. Don't fool yourselves, folks…this was a BIOWEAPON. The further we go, it will become abundantly apparent. "Bat soup" sounds like "green monkeys" to me.

  5. On 22. January Vuhan tourist have been in Milano, Verona, Venice, Zagreb, Sarajevo and Belgrade, there was news article abouth that tourists that they are no threat to public health and they were screned only for body temperature. Maybe it is coincidence and maybe not. Well see in week to come, Serbia still has no confirmed cases but I think that bus was source of virus that now show unusual big number of cases in towns that they were. We will see…

  6. You have to admit while China has certainly been controversial there approach on much of this has been proven, at least so far as the correct way.

  7. The Trump administration is requesting a billion dollars to deal with the coronavirus. I wonder how much Trump will skim off the top of that amount for his own personal cut.

  8. These numbers are VERY under reported. If you are stating these numbers you are only perpetrating CHINA CCP Propaganda.

  9. This is good news about the vaccine. It will get us to the point where we learn whether this is as difficult to vaccinate against as SARS has been. I just hope they can figure that out in animal trials instead of rushing blind into human trials.

  10. Yeh… sickness reporting has gone down in china ever since they scared anyone out of going into "quarantine" where they will definitely get the virus if they didn't already have it, and still recieve no treatment. Experts say it will peak in China at the end of April.

  11. The first thing I thought when he explained how the new vaccine is intended to work was.."wow, doctors causing autoimmune disease with vaccines ? What a shocker.". That before he even brought it up…Before anyone freaks out I'm not anti-vac …Just because we can muck-about with DNA doesn't mean we should…And isn't Genetic engineering/modifying humans suppose to illegal basically world wide?…If that's how the vaccine is to "work"..I would rather take my chances with the virus.The "cure" could be worse than the disease…Just my thoughts though.

  12. I think the TRUE mortality rate will only be known when the unseal the buildings in Wuhan…and count up the bodies…if they'll report it..
    The TRUE mortality rate can only be determined by countries like S. Korea…who have meticulously recorded the CoVid 19 Corona Virus…

  13. United States is refusing to test people who have no connection to China. You can’t have an outbreak if you don’t test genius black guy meme template

  14. WOW i never knew someone could sugar coat such a powerfull deadly disease 🦄 does he work for the WHO 😹

  15. So, that’s the Pros of the antiviral vaccine injection…Now, what are the Con(s) for getting the antiviral vaccine injection?

  16. What about the 40 cases of recovereds that get reinfection in China? I that won't be cobaia guinea pig for injection of evil RNA with 30k bases in my cells.

  17. The intro music is getting distasteful as the days pass and the news gets grimmer. New cases, new deaths, travel blog-ish intro, I kinda like it.

  18. the crazy thing about that experimental vaccine is, that the usual/conventional way seems very experimental to me – as an outsider – as well.

  19. Subunit, recombinant, polysaccharide, and conjugate vaccines use specific pieces of the germ — like its protein, sugar, or capsid (a casing around the germ). Because these vaccines use only specific pieces of the germ, they give a very strong immune response that’s targeted to key parts of the germ. They can also be used on almost everyone who needs them, including people with weakened immune systems and long-term health problems.
    One limitation of these vaccines is that you may need booster shots to get ongoing protection against diseases.

    These vaccines are used to protect against:
    Hib (Haemophilus influenzae type b) disease
    Hepatitis B
    HPV (Human papillomavirus)
    Whooping cough (part of the DTaP combined vaccine)
    Pneumococcal disease
    Meningococcal disease

  20. these videos are very interesting and informative. I'm deeply concerned about inserting virus RNA into your own cells, sounds like a bad idea, although vaccines are dead virus strains, right?

  21. "China probably prevented hundred of thousands of cases", that is blatant lie. Chinese people themselves have made videos about how the government is telling everyone o act like nothing is wrong!

  22. Sorry to say but China fucks everything up. Listen me out 70% of the viruses come from there, animal cruelty, many factories which cause global warming etc.

  23. Okay, but when the Coronavirus vaccine is available, all the hillbilly fly over state anti-vax Walmart greeter soccer moms and their kids don’t get any. Okay?

  24. Hey , should we be worry if we live in country that not evean have corona virus people and leave in a very small city 18k peaople:)?

  25. Every single bad disease came from China like the Black Death that killed more than half of the population in that time. And in my school year 8 went to Italy but we’re all sick there so they all came back home, so teachers and all the students think they have the corona virus even thou only kids get it. 🤦‍♂️🤦‍♂️🤦‍♂️

  26. Thank you. The vaccine sounds a little too scary at the moment. Has that approach been tried? What are the possible side effects? I think I would prefer self quanteening for a month till this blows over.

  27. How can the US know how many or where persons are when we are not even testing people. No temps in airports, no masks encouraged, people flying all over the world basically un checked when they return. We are not prepaired dont be fooled. We are banking on some unrealistic weird belief we are invincable. Wake up US! You say you are prepairing. Where is that again?

  28. Prediction: China will soon begin using the fictitious statistics that it is reporting to pressure other countries into removing travel restrictions and quarantine requirements on Chinese travelers. As a result, countries that give in to this pressure will see sharp increases in the spread of coronavirus in their borders.

  29. Hi Dr. Seheult : thanks for your continued quality content. When this pandemic finishes, i hope that there will be a mechanism to award people like you who help educate and inform in a consistent and fact based manner. I thank you from the bottom of my heart.

  30. This vaccine from moderna was discussed at the novel coronavirus pandemic simiulation at johns hopkins in October 2019. The vaccine is already patented. We have never used a vaccine like this.very dangerous. If this can tell your cells what to do, they can tell your brain what to do.

  31. 'Cases' are not going to show up until you get A LOT of people clearly dying from it. No one wants to be treated in the way that the Chinese government—or even the folks on the Diamond Princess—have been treated. And so the silence surrounding it will become deafening until it becomes a tsunami that we can no longer avoid. Governments need to quit being such assholes and maybe people will begin being honest about their individual situations.

  32. Just a fan here. You mention an article about a new method by injecting RNA into the body. This method you describe reminds me of the RhoGAM solution to Rh+ and Rh- partners (Rh incompatibility) when producing offspring. One potential but rare side effect is developing HIV or an HIV like virus. I'm not sure if that warning is based on screening of blood donations and the potential donor being infected with HIV or more of an RNA architecture response. Not an expert but perhaps the worst case with the new method is to develope Hemolytic anemia. Would you mind doing a video on RhoGAM and how it works? BTW, Thank You for your time and in making all of these excellent videos.

  33. Very intellectual virus when he preferred places likes this in Italy. Eclectic! No paris no london no n. York but intellectual and eclectic! Firenze Milano (gustozo!) Venezia! Whoaou!

  34. Is nobody talking about the nightmare in Iran currently with this virus? Granted I am not a big fan of Iran but this will impact many nearby countries as well. And now WHO abolishes the term "pandemic"???

  35. I live in Australia and just talked to a doctor who returned from a 10 day holiday in Italy where she toured around on a bus full of 40 people staying in hostels seeing all the public sites. The doctor was not concerned about the corona virus and had been in the area days ago that was just quarantined. The doctor is going back to her rounds in our biggest hospital. She believes that everyone will eventually get the virus but was not concerned as she is in her twenties and said she would survive it. God help us all…

  36. More and more this isn't looking to too great as this spreads. Trying to focus on the positive, the recovery rate to death rate keeps rising. As time goes on the treatments that are effective should become well known, and useable. Hopefully, we get vaccine available soon, and get it deployed to the heathcare workers to fit this virus. Best wishes to all.

  37. Chris Chapel 《China Uncensored》 Made in《China Virus》is spreading worldwide. It seems that anyone, any country who courts CCP will receive China Virus.

  38. the numbers are wrong but you overpanic… not all will get infected and maybe 10% will die, mostly old people. Thats natural selection

  39. More like the real truth is that China is still downplaying the real numbers and other countries outside are showing how this corona really moves .

  40. So 30 days back we could have tried to stop the virus by imposing travel bans. That was called too drastic. Now we have to lock down cities to prevent it from spreading and WHO says thats a good thing? So if China stops people from Wuhan to other cities(they are not even allowing people from one apartment complex in Beijing to enter another one), that's a good decision? But if other countries imposes ban from China (in Chinese cities, no one can enter anything other than his own neighborhood) or Wuhan thats too much?

  41. Like the Total recovered numbers when they just went live saying it would be atleast (at minimum) a year before a Vaccine would be available… & total deaths only account for actual deaths in hospitals, not those that died in homes, in streets or abroad

  42. I would hope that for this new type of vaccine that we have significant long term testing…the potential for something going wrong is significant

  43. I have been following all of your videos since #11. While watching this video I could follow some of the talk better since I have watched many of your previous videos. I suggest to others who have not watched past videos to do so now before continuing to watch further ones.
    I love this Channel for the informative style and information, it's my "go to" for advise. Thanks Doc.

  44. Regarding the vaccine, it seems to be safer if they make the antigens usings cells outside the body and then inject them as needed. This solves the problem of turning into an autoimmune disease.

  45. We know that alot of information outside the us is inaccurate but the info collected by the us with our infected seems to follow what china has been saying this seems like there truth isn't completely made up

  46. Talk about the US. Please tell New Yorkers to stay home when they are sick-ALL OF THEM! No masks or hand cleaners remain in NYC. New Yorkers why is that? Try to buy them if you do not believe me (incidentally if you find somewhere that has masks contact me, please!) Our markets have fallen over 2000 points since yesterday-remember the rich are catered to in this administration, (ESPECIALLY IN MI, PA, OH & FL). Every American needs to start protecting him or herself and family from this viral (no USA is not an antiviral) threat. China bought us 2 weeks and DJT threw them away!

  47. What about the whole idea in the video …of RNA being injected in humans? Risk of auto-immune disease? Who takes responsibility for that? What will the vaccine be cultured on? What will it be preserved with? Will the people have full disclosure?

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